Thursday, November 7, 2019
Writing in the Electronic Age essays
Writing in the Electronic Age essays Although Lev Manovich presents several relevant issues in his essay, his work was utterly impossible to understand. After days of blank stares at incomprehensible words, I finally had a breakthrough. Could he be discussing databases in relation to our everyday lives and new media? That is exactly what he is saying, just in ten pages longer than it really had to be. In the first few dozen pages of his work, Manovich discusses narrative style. Narrative style tends to be a linear, or chronological, way of explaining an event or process. Typically this is done orally in the form of a story. Narrative style is syntagmatic, or following a natural order. The story is easy to understand and normally is arranged chronologically. For example, when someone is describing their day, they would explain the highlights in chronological order using narrative style. Another way Manovich thinks we present information is by the use of database. He defines databases as a structured collection of data. Databases can be linear or non-linear. Simply put they are files of information stored in a computer. The information is easily retrievable, but is not in chronological order. Instead it is situated using paradegmatic form, which is organization into natural categories. For example, if a database were used to organize my life story, there would be individual files for my birth, childhood, public schooling, and college. Of course more would be added as my life went on. There are few similarities between narrative and database forms. They both communicate to the reader, or viewer, with words or images and try to, as Lev Manovich states, "make meaning out of the world." Being competitors they tend to contrast each other in many aspects while fighting for dominance in the field. Narratives follow a certain order, usually linear, and have explainable reason behind that particular order. Databases have a random order, but all the individual files have so ...
Tuesday, November 5, 2019
The Laws of Thermodynamics in Biological Systems
The Laws of Thermodynamics in Biological Systems The laws of thermodynamics are important unifying principles of biology. These principles govern the chemical processes (metabolism) in all biological organisms. The First Law of Thermodynamics, also known ââ¬â¹as the law of conservation of energy, states that energy can neither be created nor destroyed. It may change from one form to another, but the energy in a closed system remains constant. The Second Law of Thermodynamics states that when energy is transferred, there will be less energy available at the end of the transfer process than at the beginning. Due to entropy, which is the measure of disorder in a closed system, all of the available energy will not be useful to the organism. Entropy increases as energy is transferred. In addition to the laws of thermodynamics, the cell theory, gene theory, evolution, and homeostasis form the basic principles that are the foundation for the study of life. First Law of Thermodynamics in Biological Systems All biological organisms require energy to survive. In a closed system, such as the universe, this energy is not consumed but transformed from one form to another. Cells, for example, perform a number of important processes. These processes require energy. In photosynthesis, the energy is supplied by the sun. Light energy is absorbed by cells in plant leaves and converted to chemical energy. The chemical energy is stored in the form of glucose, which is used to form complex carbohydrates necessary to build plant mass. The energy stored in glucose can also be released through cellular respiration. This process allows plant and animal organisms to access the energy stored in carbohydrates, lipids, and other macromolecules through the production of ATP. This energy is needed to perform cell functions such as DNA replication, mitosis, meiosis, cell movement, endocytosis, exocytosis, and apoptosis. Second Law of Thermodynamics in Biological Systems As with other biological processes, the transfer of energy is not 100 percent efficient. In photosynthesis, for example, not all of the light energy is absorbed by the plant. Some energy is reflected and some is lost as heat. The loss of energy to the surrounding environment results in an increase of disorder or entropy. Unlike plants and other photosynthetic organisms, animals cannot generate energy directly from the sunlight. They must consume plants or other animal organisms for energy. The higher up an organism is on the food chain, the less available energy it receives from its food sources. Much of this energy is lost during metabolic processes performed by the producers and primary consumers that are eaten. Therefore, much less energy is available for organisms at higher trophic levels. (Trophic levels are groups that help ecologists understand the specific role of all living things in the ecosystem.) The lower the available energy, the less number of organisms can be supported. This is why there are more producers than consumers in an ecosystem. Living systems require constant energy input to maintain their highly ordered state. Cells, for example, are highly ordered and have low entropy. In the process of maintaining this order, some energy is lost to the surroundings or transformed. So while cells are ordered, the processes performed to maintain that order result in an increase in entropy in the cells/organisms surroundings. The transfer of energy causes entropy in the universe to increase.
Saturday, November 2, 2019
Response Paper #3 Essay Example | Topics and Well Written Essays - 1000 words - 1
Response Paper #3 - Essay Example The short story ââ¬ËRecitatifââ¬â¢ by Toni Morrison brings out the racial relations in America even after the country became free and slavery was system was destroyed. The story essentially focuses on the friendship between two girls of opposite races meeting as children. They meet at St. Bonnyââ¬â¢s and are roommates. They are similar in many ways. The most ambiguous part is the identification of their race, which is not clearly mentioned for any of them. Initially it seems that Twyla is white and Roberta is black but later in the middle of the story it seems the opposite and then again the vision somewhat changes towards the end of the story. However after careful examination of the details one would say that Roberta is black. The most important part here is the racial difference. The difference is so severe that it is carried over to the children in schools. Towards the end of the story one finds the mothers (racially opposite groups) fighting for their rights. The story outlines the typical life style of an Afro-American girl who drops in and out of school and could not read. She (Roberta) is taken to drugs and wears large earrings, curls and has an appointment to meet Jimi Hendrix, a black singer. However when she meets Twyla after several years, she behaves coldly towards her. Later she explains it was because of the racial social structure ââ¬âââ¬Å"Twyla, you know how it was in those days: black-white. You know how everything wasâ⬠(Morrison, 255). The inner bonding between the two girls is quite strong and prominent but the social structure prevents them from free expression of the affection they share. They make it up in the end and Roberta, who accused Twyla of kicking a black woman Maggie (who perhaps was not black at all), clarifies her mistake to Twyla and explains that she need not carry the guilt anymore. The friendship
Thursday, October 31, 2019
Advances in Wireless Networks Essay Example | Topics and Well Written Essays - 2500 words
Advances in Wireless Networks - Essay Example This network will be a controller-based wireless LAN technology that will be used to modernize the daily tasks University of Iland (UoI). This report outlines the specification and design of the new network. Introduction In this report I am going to specify a new controller-based wireless LAN design for University of Iland. The management of University of Iland wants to revolutionize the new technology based processes and network of university. This new technology based infrastructure will offer an excellent support for the potential working and improve performance of university learning, data sharing and educational performance. This specification report will present a comprehensive analysis and specification of new wireless network technology, its requirements, design, systems, equipment and computations required for the establishment of LAN network at University of Iland. Aims and Objectives The key aim and objective of this new wireless technology based structure is to develop an d implement a new technology based framework at University of Iland that will support the Schoolââ¬â¢s Information Technology strategy for the next seven to ten years. This report is aimed at offering a detailed analysis of specification and procurement activities for the implementation of new wireless LAN based Information technology structure.... Structure of the School The school has seen rapid growth in the past five years, particularly after acquiring local consultancy contracts and attracting national research projects. There are many subject groups within the school such as Networks, Artificial Intelligence, Systems Analysis, Design and Informatics, Software engineering and E-Business. P.E. Ryno is the Dean of the School; there are many group leaders subordinate to him. In this scenario, the newly established school of computing has following structure of the subject groups within the school: No- Subject Groups Members of staff 1 Networks group 5 members 2 Artificial Intelligence group 4 members 3 Software engineering group 5 members 4 E-Business group 5 members 5 Admin group 5 members 6 Technicians group 5 members 7 Group Leader Informatics 6 members 8 Group Leader for the technicians 6 members In the context of future growth of present educational structure we are expecting more staff members connecting to network and communication arrangement. It is anticipated that approximately 10-12 members of staff will join this school in the next 5 years Technology Needs Specification There are many system related needs and requirements. This part of report will outline main technologies that will be implemented at University of Iland through the establishment of new information and networking technology structure. For sake of this new technology specification, I will outline some of the main needs of the school network technology. Personal Computers The personal computer will be available to all members of the school staff. These systems will include some of the modern laptops.
Tuesday, October 29, 2019
American culture Essay Example | Topics and Well Written Essays - 500 words - 1
American culture - Essay Example n and continue to be acquired and get integrated as parts of our own culture mostly this is through mass media in music and movies, as well as social network. These include positive philosophies like the believe in their rights, patriotism as well as the negative aspects such as popular drug and substance abuse and certain hedonistic elements especially pertaining to youths and sex. In this paper, I will discuss aspects of American culture that I would like to have acquired in my country as well as those I hope will never become part of my countries culture. Respect for the rights of others is the embodiment of American way of life, through the mass media, we hear about Americans having the right to express themselves as long as they do not interfere with othersââ¬â¢ freedom, live anywhere, marry anyone they want their sexual orientation, and often make designs about abortion. World over, Americans are known for agitating for their rights, and I believe that having citizens aware and understanding their rights is something from which my country can benefit. The nationalism of the American people is another admirable attribute of the American culture they are very patriotic, and this is evident in their music and from the mass media especially through political campaigns. The success of songs like Springsteenââ¬â¢s born in the USA and Kanyeââ¬â¢s American Boy are a tribute to the high levels of patriotism in the USA (Hilker). The political campaigns are the embodiment of nationalism and the leaders often deal with people centere d issues such as health and economic growth. Nonetheless, I consider some negative aspects of American culture undesirable, and I would hope they do not become a part of my countries culture. One of this is the casual way in which the youth seem to treat the subject of drugs, especially Marijuana in many American movies such as American, pie and the more recently, ââ¬Å"Harold and Kumarâ⬠. Some of the characters are seen smoking weed ââ¬Å"as a
Sunday, October 27, 2019
About Cervical Cancer
About Cervical Cancer Abstract: Cervical cancer is the second most common cause of cancer death in developing countries. The cause of cervical cancer is the human papilloma virus (HPV). Cervical cancer has other risk factors, like: having multiple male sexual partners, starting to have sexual intercourse at an early age, having other sexually transmitted disease, having weak immune system and smoking. Cervical cancer can be prevented by avoiding risk factors and undergoing regular screening tests. The most common methods used in cervical screening are Pap testing and HPV testing. World Health Organization estimated that about 510,000 new cases of cervical cancer were diagnosed yearly. HPV testing is used as a primary screening method in some developed countries. Fewer amounts of tests required and better cost efficiency can be achieved by doing HPV testing first and Pap testing as a second test. Some studies suggested that HPV testing might be the effective cervical screening method and other studies did not suggest that. The study HPV Screening for Cervical Cancer in Rural India indicated that HPV testing was the most objective and reproducible of all other cervical screening tests. It seems to be a good study with well designed methodology and reliable results and conclusions, but it was criticized by R Marshall and Chengquan. They showed clearly that the study marred by test group biases and ethical concerns. More well designed studies are needed to clarify this issue and to show which method is proper to that country or to this geographical area. Introduction: Cervical cancer is the cancer of the lowest part of the uterus, which is known as cervix. Cervical cancer is very slow growing, but in some cases it can grow and spread quickly (Dolinsky Hill-Kayser, 2009). There are many types of cervical cancer. The most common type is called squamous cell carcinoma (figure 1), which found in about 80% of cervical cancer cases, whereas adenocarcinoma is the second most common type of cervical cancer (Dolinsky Hill-Kayser, 2009). Cervical cancer is more common in developing countries than it is in developed countries. It is the second most common cause of cancer death in developing countries. It can affect young women who are 20 years old or some time younger than that (Dolinsky Hill-Kayser, 2009). The cause of cervical cancer is the human papilloma virus (HPV) (figure 2) which was discovered by Harald zur Hausen who won the Nobel Prize in 2008 for this discovery (Nobel Prize organization, 2009). This virus is a sexually transmitted virus. It can cause genital warts which may or may not change to a cervical cancer (Dolinsky Hill-Kayser, 2009). The subtypes of HPV which have been confirmed to cause cervical cancer are 16, 18, 31 and 33 (Murray et al., 1998; Dolinsky Hill-Kayser, 2009). Other researches suggested that subtypes 35 and 45 also can cause cervical cancer (NHS cancer screening programmes, 2009). A woman has HPV infection does not mean that she is going to have a cervical cancer (Dolinsky Hill-Kayser, 2009). Other risk factors for cervical cancer are: having multiple male sexual partners, starting to have sexual intercourse at an early age, having other sexually transmitted disease (herpes, syphilis, gonorrhea or Chlamydia), having weak immune system (HIV, organ transplantation or Hodgkins disease) and smoking (Dolinsky Hill-Kayser, 2009). The early stages of this disease usually do not have any symptoms, but as tumor increase in size, some non-specific symptoms for cervical cancer will occur, like: abnormal bleeding, abnormal vaginal discharge, pelvic or back pain, pain during urination and bloody stool or urine (Dolinsky Hill-Kayser, 2009). Cervical cancer can be diagnosed by Pap testing, HPV testing, liquid-base cytology and by taking a biopsy during Colposcopy. The biopsy is the only way to be sure if the patient has a cervical censer. Radiologic testing may also help in the diagnosing of this disease (Dolinsky Hill-Kayser, 2009). Cervical cancer can be treated by Surgery, radiotherapy and chemotherapy (Dolinsky Hill-Kayser, 2009). It can be prevented by avoiding risk factors which have been discussed previously and undergoing regular screening tests (Dolinsky Hill-Kayser, 2009). In Islam religion for example, smoking and any sexual relationship not done between wives and husbands (reducing sexually transmitted diseases) are strictly forbidden, this can reduce the chance of having cervical cancer within Muslim societies (Adam, 2009). In addition, male circumcision which is a part of Islam religion has found to be a good factor in cervical cancer prevention as researches have found that the wives of circumcised men have less risk of getting this disease than the wives of uncircumcised (Mission Islam, 2009). Moreover, many countries have started to do cervical cancer screening to diagnose this disease in its early stages. Pap testing (cytological testing), HPV testing and liquid-base cytology can be used in this screening programs which will be discussed later (Kufe et al., 2003; Jamison et al., 2006). Now a day, the vaccine Gardasil is used to prevent cervical cancer in women who are not exposed to HPV (Dolinsky Hill-Kayser, 2009). This study is aimed to discus the importance of HPV screening in the control of cervical cancer and clarifies the most appropriate method for cervical cancer screening. The Global Burden of Cervical Cancer and the Available Methods for Controlling the Disease: Cervical cancer is the second most common cancer among females worldwide with about 493,000 new cases and 274,000 deaths in 2002. Cases occur in developing countries are estimated to be about 83% (Bosch et al., 2009). Thomas Rohan and others stated that opportunities for cervical cancer prevention have been created by our understanding of the cause, particularly the role of HPV infection (Rohan et al., 2003). In addition, World Health Organization estimated that about 510,000 new cases of cervical cancer were diagnosed yearly. In Africa, about 68,000 new cases are reported every year, whereas 77,000 new cases are reported in Latin America and 245,000 in Asia (Pagliusi, 2009). In United Kingdom, about 25.51 millions females who are 15 years old are at risk of having a cervical cancer during their life. This kind of cancer is ranked as the 11th most common cancer in females in UK and the 2nd most common cancer in females between 15 and 44 years old. In addition, about 8.9% of females in the population of UK are estimated to have HPV infection at a given time. Currently in UK, it is estimated that about 3181 females are reported with a cervical cancer yearly and about 1529 deaths (Bosch et al., 2009). Many researches suggested that the decline in incidence and mortality of cervical cancer which have been observed in the last 50 years in developed countries can be related to the introduction of screening programs (Kufe et al., 2003). The most common methods used in cervical screening are Pap (cytological) testing and HPV testing (Kufe et al., 2003). The most widely used method in the world is the Pap testing. This method is simple, cheap and some times is used as a secondary screening method. It basically involves exfoliating epithelial cells collection from the squamocolumnar junction of cervix or transformation zone (Walker et al., 1990; Kufe et al., 2003). In addition, HPV testing is used as a primary screening method in some developed countries. It is used mostly to distinguish between a high risk women group and others (Kufe et al., 2003). The study of Joakim Dillner and others suggested that HPV testing as a screening method is safe and effective when it is done every six years (Dillner et al., 2008) and it should be done for women who are 30 years old or older because they are typically past the peak age of self-limited infection (Castle, 2008). HPV DNA testing might be a more clinically effective method than cervical smear, but its specificity is low because it could lead to unnecessary repeated screening and follow up (Nelson (I), 2009). Fewer amounts of tests required and better cost efficiency can be achieved by doing HPV testing first and Pap testing as a second test (Medscape Medical News, 2009; Nelson (I), 2009). Existing Randomized Controlled Trails Investigating the Use of HPV Testing in the Control of Cervical Cancer: Many randomized controlled trails have been done to investigate the use of HPV testing in the control of cervical cancer. Some studies suggested that HPV testing might be the effective cervical cancer screening method (Grce and Davies, 2008; Rebar, 2008; Nelson (II), 2009). On the other hand, other studies suggested that HPV testing does not improve cervical cancer screening (Brown, 2009; NHS cancer screening programs, 2009). In Italy, the second recruitment phase of the study titled: New Technologies for Cervical Cancer Screening (NTCC), women to conventional cytology (24,661 women) with referral to colposcopy if cytology indicated a typical squamous cells of undetermined significance or more sever abnormality or to HPV DNA testing alone by Hybrid Capture 2 (24,535 women) with referral to colposcopy if the test was positive at a concentration of HPV DNA 1 pg/mL or greater were randomly assigned. It has been concluded that HPV testing with a cutoff of 2 pg/mL achieves a substantial gain in sensitivity compared to cytology with only a small reduction in Positive Predictive Value among a group of women aged 35 to 60 years. In contrast, for women aged 25 to 34 years, it is suggested that there is a frequent regression of CIN2+ that is detected by direct referral of younger HPV testing-positive women to colposcopy as a result of the large relative sensitivity of HPV testing compared with conventional cytology (Ronco et al., 2008). In addition, the results from a 6-year prospective study in Rural China demonstrated that a single oncogenic HPV DNA testing is more effective than cytology in predicting future CIN2+ status (Shi et al., 2009). The study Human Papillomavirus DNA versus Papanicolaou Screening Tests for Cervical Cancer which was done in Canada, conducted a randomized trial comparing the two methods, found that HPV testing has greater sensitivity than Pap testing for the detection of cervical intra-epithelial neoplasia (Mayrand et al., 2007). The Population Based Screening Study Amsterdam (POBASCAM) which is a population based randomized controlled trial for implementation of hrHPV testing by GP5+/6+ PCR-enzyme immunoassay (EIA) with a classical cytology as a control group was done between January 1999 and September 2002. It was done among 44,102 women aged between 29 and 61 who participated in the regular Dutch screening program. This study (POBASCAM) indicated that large scale hrHPV testing is accepted by both participating women and general practitioners, is practically feasible and yield highly reproducible results (Bulkmans et al., 2004). In 1997, a 10-year study Randomized Controlled Trial of Human Papillomavirus Testing in Primary Cervical Cancer Screening (SWEDESCREEN) was started. This study aimed to investigate whether HPV-based cervical cancer screening which is known to increase sensitivity for detection of high grade cervical intraepithelial neoplasia (CIN) is represent overdiagnosis or a protective effect. It included 12,527 women aged between 32 and 38 years and were randomized (1:1) to HPV testing and cytology testing (intervention arm) or cytology only (control arm). Its conclusion indicated that HPV testing with a cytology testing is more sensitive than cytology testing alone (U.S. National Institute of Health, 2009). In another study, titled Randomized Controlled Trial of Human Papillomavirus Testing Versus Pap Cytology in the Screening for Cervical Cancer Precursors, the Canadian Cervical Cancer Screening Trial (CCCaST), randomized women aged between 30 and 69 years were categorized in to Pap testing group and HPV testing group. The findings at recruitment phase of this study indicated that HPV testing is more sensitivity and less specificity than Pap cytology testing (Mayrand et al., 2006). An Overview on the Methodology, Results and Conclusions of the Study: HPV Screening for Cervical Cancer in Rural India: Rengaswamy and others began their study HPV Screening for Cervical Cancer in Rural India in 1999 and finished after 8 years. In this study, 52 clusters of villages with a total of 131,746 healthy women aged between 30 and 59 years were randomly assigned to 4 groups of 13 clusters each. These groups assigned to go through screening by: HPV testing group (34,126 women) (27,192 were screened and 2812 (10.3%) had positive results). Cytology testing group (32,058 women) (25,549 were screened and 1787 (7.0%) had positive results). Visual Inspection of the Cervix with Acetic Acid (VIA) group (34,074 women) (26,765 were screened and 3733 (13.9%) had positive results). Standard care group (control) (31,488 women) (not offered screening but were advised on how to seek screening) (only 1946 (6.2%) requested screening and that means (93.8%) stayed without screening. Women who had positive results went through colposcopy and biopsies were taken and those with cervical precancerous lesions or cancer received appropriate treatment (Sankaranarayanan et al., 2009). The results of this study showed that:à In HPV testing group: cervical cancer was diagnosed in 127 women and 34 deaths occurred. In Cytology testing group: cervical cancer was diagnosed in 152 women and 54 deaths occurred. In VIA group: cervical cancer was diagnosed in 157 women and 56 deaths occurred. In Control group: cervical cancer was diagnosed in 118 women and 64 deaths occurred. In addition, this study indicated that of the 131,806 women, 60 died or migrated before the study began. The study groups were equally distributed in terms of household type, religion, occupation, marital status and number of pregnancies. The well balanced study will help to remove any biases to any group of the study. The results of this study showed also: Invasive cervical cancer developed in 8 (0.033%) of 24,380 HPV negative results women. Invasive cervical cancer developed in 22 (0.093%) of 23,762 cytology negative results women. Invasive cervical cancer developed in 25 (0.109%) of 23,032 VIA negative results women (Sankaranarayanan et al., 2009). The protocol of this study was reviewed and approved by the scientific and ethical review committees of the International Agency for Research on Cancer (IARC), the Tata Memorial Center (TMC) and the Nargis Dutt Memorial Cancer Hospital (NDMCH). It was supported by the Bill and Melinda Gates Foundation through the Alliance for Cervical Cancer Prevention (Sankaranarayanan et al., 2009). This study concluded that a single round of HPV testing was associated with a significant decline in the rate of advanced cervical cancers and associated deaths compared with the unscreened control group, whereas there was no significant reduction in the rate of death in either the cytology testing or the VIA group compared with the control group. Previous conclusions indicated that HPV testing was the most objective and reproducible of all other cervical screening tests (Sankaranarayanan et al., 2009). This study seems to be a good one with well designed methodology and reliable results and conclusions, but it is clear that about 93.8% of the control group did not do any cervical screening during the 8 years which may raised an ethical issue might affecting the approval of this study if it was done in different country. Further more, the courses and training period given to different staffs who participated in this study may be not enough to give them good experience in order to have less chance of error during the diagnosis. An Overview on the Criticizing Article Titled: Test Group Biases and Ethical Concerns Mar New England Journal of Medicine Articles Promoting HPV Screening for Cervical Cancer in Rural India:à A few months after the publication of previous study, R Marshall and Chengquan had criticized it. They suggested that unexpected biases might have occurred in some of the test groups of the study. The study stated that the positive predictive value for detecting CIN 2-3 was 19.3% in the cytology testing group, higher than 11.3% in the HPV testing group and the study results indicated that essentially the same number of cervical cancers was detected after positive screening test results in the cytology group (88 women) and in the HPV group (87 women) (Austin Zhao, 2009). Also, they observed that in the report of 2005, this study indicated that the detection rates of HPV testing did not show any improvement over cytology, but its conclusion of 2009 indicated different findings (Austin Zhao, 2009). I think this is not a problem as findings and conclusions of scientific studies usually change over time. In addition, of 54 cervical cancers related deaths in the cytology group, 27 deaths were in the assigned but not screened group and another 18 deaths were in patients who had abnormal cytology results. In HPV group, 19% fewer cervical cancer deaths (22 women) were in the assigned but not screened group and 33% fewer deaths (12 women) occurred in women with abnormal HPV testing results. These data supported the hypothesis that biases were introduced in the study groups. (Austin Zhao, 2009). I think it is possibly true, because these data can show that the follow up and treatments were not equally effective in the two groups. So, even when cytological detection is successful, women can still die from cervical cancer due to inappropriate management. In addition, these data also can show that the effectiveness of cytology as a cervical screening method is depended on its acceptance by women.à R Marshall and Chengquan have raised questions about the partnership between AACPs coordinating organization and the HPV test manufacturer (Austin Zhao, 2009). I think this partnership if it is real, it can affect the final results and conclusion in way that show the advantages of HPV testing in order to increase the income of the manufacture. Also they stated that it is not fare to allow a large number of control group to go without any screening during the study (Austin Zhao, 2009). I think it is true that it is not fare to leave women in the control group without any screening and this can lead to ethical concerns. In addition, cytology screeners were trained for only three months, which was very short period. They concluded that cytology screening is better than HPV screening according to the results of the previous study (Austin Zhao, 2009). In my opinion, the criticizing letter might be in the correct direction. From a brief reading and viewing of the study, the reader might believe that its finding indicated that HPV testing as a cervical cancer screening method is better than other tests, but deep reading will show him the limitation errors of this study which were firstly published by R Marshal and Chengquan. They showed clearly that the study marred by test group biases and ethical concerns. The study might try to cover and exclude some facts which can show that cytology testing was better than HPV testing. Use or Not to Use HPV Testing as a Primary Screening Test for Cervical Neoplasia: It has been argued that HPV testing is the best method for cervical cancer primary screening. I think that HPV testing is a good method to be used in cervical cancer primary screening in developing countries as well as in developed countries to reduce the incidence and mortality rates of cervical cancer. Studies which concluded that HPV testing is better than cytology testing are more than those which showed the opposite. The high cost of HPV testing can be overcome by the support of WHO and privet sector companies in these developing countries. Also, the high cost of HPV testing can be overcome by the selective use of HPV testing, e.g. in the over 30s. Many studies suggested that Human Papillomavirus is found in most of cervical cancer cases if not all. So, the use of HPV DNA testing in a well designed screening program may help in diagnosis early stages of cervical cancer, giving better chance for treatment compared with Pap testing which may give false negative results. à à In conclusion, it is clear that different results and findings were gathered from different studies which try to find the proper method for cervical cancer screening. These differences may be occurred because the studies done in different countries. And is it known that each country has its own geography, rate of mortality, rate of incidence and other factors which may affect the burden of cervical cancer disease. So, more well designed studies are needed to clarify this issue and to show which method is proper to that country or to this geographical area in order to save womens lives. References: Adam, A. (2009), Sexually Transmitted Diseases and Islam. Kuwait.à Available from: http://www.islamset.com/hip/anvir_adam.html [Accessed 30-11-2009]. Austin, R. M., Zhao, C. (2009), Test group biases and ethical concerns mar New England Journal of Medicine articles promoting HPV screening for cervical cancer in rural India. CytoJournal, 6 (12), pp. 1-5. Bosch, F. X., Castellsague, X., Sanjose, S., Alarcon, F., Albero, G., Bruni, L., Ferrer, E., Louie, K. S., Miralles, C., Monfulleda, N., Munoz, J., Perez, S., Rajo, C., Roura, E. (2009), Human papillomavirus and related cancers. United Kingdom, WHO/ICO Information Centre on HPV and Cervical Cancer.à Available from: http://apps.who.int/hpvcentre/statistics/dynamic/ico/country_pdf/GBR.pdf?CFID=278048CFTOKEN=18959369 [Accessed 1-12-2009]. Brown, A. J. (2009), HPV testing does not improve cervical cancer screening. The Lancet Oncology, 16 (52), pp. 02 -0400. Bulkmans, N. W. J., Rozendaal, L., Snijders, P. J. F., Voorhorst, F. J., Boeke, A. J., Zandwijken, G. R., van Kemenade, F. J., Verheijen, R. H., Groningen, K., Boon, M. E., Keuning, H. J., van Ballegooijen, M., van den Brule, A. J., Meijer, C. J. L. M. (2004), POBASCAM, a population-based randomized controlled trial for implementation of high-risk HPV testing in cervical screening: design, methods and baseline data of 44,102 women. International Journal of Cancer, 110, pp. 94-101. Castle, P. E. (2008), Invited commentary: is monitoring of human papillomavirus infection for viral persistence ready for use in cervical cancer screening. American Journal of Epidemiology, 168 (2), pp. 138-144. Dillner, J., Rebolj, M., Birembaut, P., Petry, K. U., Szarewski, A., Munk, C., Sanjose, S., Naucler, P., Lloveras, B., Kjaer, S., Cuzick, J., Ballegooijen, M., Clavel, C., Iftner, T. (2008), Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study. British Medical Journal, 337 (1754), p. a1754. Dolinsky, C., Hill-Kayser, C. (2009), Cervical Cancer: The Basics. United States of America, Abramson Cancer Center of the University of Pennsylvania. Available from: http://www.oncolink.org/types/article.cfm?c=6s=17ss=129id=8226p=1 [Accessed 30-11-2009]. Grce, M., Davies, P. (2008), Human papillomavirus testing for primary cervical cancer screening. Expert Review of Molecular Diagnostics, 8 (5), pp. 599-605. Jamison, D. T., Breman, J. G., Measham, A. R., Alleyne, G., Claeson, M., Evans, D. B., Jha, P., Mills, A., Musgrove, P. (eds.) (2006), Disease Control Priorities in Developing Countries.à Washington: The World Bank and Oxford University Press. Kufe, D. W., Pollock, R. E., Weichselbaum, R. R., Bast, R. C., Gansler, T. S., Holland, J. F., Frei III, E. (eds.) (2003), Cancer Medicine. Canada: BC Decker Inc. Mayrand, M. H., Duarte-Franco, E., Coutlee, F., Rodrigues, I., Walter, S. D., Ratnam, S., Franco, E. L. 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Friday, October 25, 2019
Analysis of Transaction Processing Systems :: Computer Science Technology Essays
Analysis of Transaction Processing Systems It is the processing in which a system respond to a userââ¬â¢s command to carry out some operation to and fro. The request or command is called TRANSACTION, and the system carrying it out is called TRANSACTION PROCESSING SYSTEM e.g cash machines. Transaction processing systems are the systems working at a low level of any organizational structure being operated by data entry operators etc to collect and store data which is needed to be transported then to decisional level of organisations. But it is important to make sure nothing goes wrong at this level of handling data before it is transported to upper level to be manipulated and then making decisions based on information provided. ââ¬Å"There is some support for the propositions that (1) Transaction processing systems should be able to be managed within each work group in an organisation, managed that is with respect to work stations in use and functionality available on those workstations. (2) exhibit very little model behaviour. (3) support a high degree of operator independence or asynchornity.â⬠REFERNCE: http://www.csse.monash.edu.au/~cavram/papers/tp/tr94-02h.html There are 9 types of transaction processing models 1: Batch systems: 2: Monitor systems : 3: Time sharing systems 4: Advanced virtual terminal front end systems 5: Client server systems 6: Electronic mail and forms 7: Database based groupware 8: (IVR) systems 9: (EDI) systems ââ¬Å"Transaction processing systems are information systems which collect data and distribute operational data both within and between organisations. The wide spread use of networks and personal computers (used as terminals) has provided feasible new options for the design of transaction processing systemsâ⬠b. DECISION SUPPORT SYSTEMS: ââ¬Å"Decision Support Systems (DSS) are a class of computerized information systems that support decision-making activities. DSS are interactive computer-based systems and subsystems intended to help decision makers use communications technologies, data, documents, knowledge and/or models to successfully complete decision process tasksâ⬠Reference: http://dssresources.com/ Decision support systems are the computer information application which collects and analyze data and then present it to the decision making people of organisation i.e managers . decision support system as the name suggest help and support managers to make effective ,right and timely decisions. These systems store and process data at a much higher and efficient speed and then represent the information in multiple forms which could be regular text , graphical representation, numerical etc which really enable managers to come up with timely and right decisions. As the decision makers could be different so can be the systems as some work individually while other work in teams there are differences in decision contexts, types, and makers. ââ¬Å"There are certain common traits that decision-making processes tend to exhibit. They typically involve the phases of intelligence, design, and
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